:dex:

If you have an ATI/AMD graphics card, it's possible using Catalyst profiles. Create two profiles in the Catalyst Control Center, one landscape and one portrait. Then add commands like this in "Configure Desktops > Start-Up" when entering/leaving the appropriate desktops:

[code]"C:\Program Files\ATI Technologies\ATI.ACE\Core-Static\cli.exe" Start Load profilename="NameOfProfile"[/code]
For your example, load the portrait profile on every entry of Desktop 3 and the landscape profile on every exit of Desktop 3.

Would there be a way to implement a different orientation per desktop selected?

Say I wanted to open and read a pdf book on VD3 set in portrait orientation, while VD1, VD2, and VD4 are still in landscape mode.

I know there are physical issues with switching the orientation that often, but there are things to make that easier.

I don't need the resolution changing ability, just the orientation switching.